Conference Summary

This conference is the first of its kind to convene researchers focused on experience-regulated transcription in the brain. The study of experience-regulated transcriptional plasticity is at the forefront of technological developments within the disciplines of molecular biology, biochemistry, and genomics. This conference will be relevant to research into several human disorders and diseases associated with both inefficient gene transcription and mutations in genes. 

The inaugural program will present the latest findings from scientists with distinct approaches to experience-dependent transcriptional regulation. Sessions will discuss new methods for studying transcription, functions of activity-regulated transcription in development and disease, and mechanisms of activity-regulated gene transcription in neurons.

Attendees will learn about:

· Molecular genetics and genomics of activity-regulated gene transcription and translation.

· The role of transcription in learning, memory, and synaptic plasticity

· Dysregulation of transcription in developmental disorders and aging

· Discoveries and technologies to study excitation-transcription coupling. 

Program Topics

· All IEGs are not created equal

· Activity-dependent genomic mechanisms

· Hot topics in neural epigenetics

· New methods for studying activity-regulated transcription

· Transcriptional regulation of synapses

· Transcriptional regulation of sensory processing and circuit plasticity

· Learning and memory

· Transcriptional and epigenetic regulation of maladaptive plasticity 

Workshops

A Meet the Experts lunch session will feature a broad cross-section of senior scientists, including journal editors, NIH staff, industry representatives, and academic researchers, who will discuss their experiences with early-career researchers. 

A series of Career Development Workshop roundtables will feature conversations led by established investigators on career topics, including finding a postdoc, the paper writing process, mentoring, and career placement. 

Keynote Speakers

Michael Greenberg, PhD

Michael Greenberg, PhD
Nathan Marsh Pusey Professor of Neurobiology
Harvard Medical School
Boston, MA

Richard Tsien, PhD

Richard Tsien, PhD
Druckenmiller Professor of Neuroscience
NYU Grossman School of Medicine
New York, NY

Organizers

Anne West, MD, PhD

Primary Organizer: Anne West, MD, PhD
George Barth Geller Professor of Neurobiology
Duke University
Durham, NC

Ramendra Saha, PhD

Ramendra Saha, PhD
Associate Professor of Molecular and Cellular Biology
University of California
Merced, CA

Ivo Spiegel, PhD

Ivo Spiegel, PhD
Associate Professor of Brain Sciences
Weizmann Institute of Science
Rehovot, Israel

Important Dates

Abstract Submission Deadline: Monday, August 10, 2026

Early Registration Deadline: Monday, August 17, 2026

Housing Deadline: Monday, September 14, 2026

Registration Cancellation Deadline: Monday, September 14, 2026

Regular Registration Deadline: Monday, September 28, 2026

Attendance Request 

Email template with talking points

Venue

The Crowne Plaza Melbourne-Oceanfront is located in Melbourne, Florida, on the Atlantic Coast. Experience adventures with the beach just steps away, free wifi, and a free hotel shuttle.

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