Conference Summary

Since 2010, this essential conference has focused on the field of genome and epigenome editing, as well as the newest engineering technologies used in the field. This year’s program will present findings on genome editing outcomes, pre-clinical translation of editing technologies, in vivo delivery of genome editors, and clinical trials of genome editors. 

Genome editing technologies are rapidly becoming some of the most promising discoveries in the history of genetics. Treatments presented at this conference have received approval for patient use in the U.S. and Europe, including exa-cel, an ex vivo autologous, genome-edited cell therapy for sickle cell disease. Also previously discussed at this SRC, a promising in vivo personalized genome editing medicine was rapidly developed and successfully administered to treat an infant with a rare genetic disease.

Attendees will learn about:

· Genome editing technologies and their applications to research and medicine.

· How genome and epigenome editing strategies are being translated for clinical applications.

· Late-breaking technologies related to precise genome and epigenome editors.

Program Topics

· Genome and epigenome engineering technology

· Biology of DNA repair and genomics of genome and epigenome editing outcomes

· Pre-clinical translation of genome and epigenome editing

· Towards personalized genome editing

· In vivo delivery of genome editors

· Plant and animal genome editing

· Clinical trials of genome and epigenome editors

Workshops

A Meet the Experts session will be held during a lunch session, during which early-career researchers participate in small-group discussions with leading speakers and senior investigators from academia and industry.

The Career Development Workshop will feature panelists from academia and industry, discussing their career trajectories in an informal setting. The session will include a Q&A for an honest discussion of the challenges researchers face in their careers and how to navigate them.

Keynote Speaker

Luigi Naldini, MD, PhD

Luigi Naldini, MD, PhD
Director
San Raffaele Telethon Institute for Gene Therapy
Milan, Italy

Organizers

Shengdar Tsai, PhD

Primary Organizer:
Shengdar Tsai, PhD, Associate Member, St. Jude Children's Research Hospital, Memphis, TN

Nicole Gaudelli, PhD

Nicole Gaudelli, PhD
Entrepreneur in Residence
Google Ventures
Cambridge, MA

Philip Gregory, PhD

Philip Gregory, PhD
Head of Regeneron Cell Medicines
Regeneron
Cambridge, MA

Angel Lombardo, PhD

Angelo Lombardo, PhD
Professor
Vita-Salute San Raffaele University, Milan, Italy

Important Dates

Extended Abstract Submission Deadline: Monday, May 25, 2026

Early Registration Deadline: Monday, May 25, 2026

Housing Deadline: Monday, June 6, 2026

Registration Cancellation Deadline: Monday, June 15, 2026

Regular Registration Deadline: Monday, June 29, 2026

Attendance Request 

Email template with talking points

Venue

Located in the heart of the business district, the Sheraton Porto Hotel & Spa offers you the opportunity to immerse yourself in Porto, a unique, exquisite and authentic destination. Like its wine, the city is a treasure to be slowly appreciated. Enjoy the convenience of being only a short distance away from the city’s rich heritage, where you connect with 800 years of history.

Sign Up for Event Updates