Conference Summary

Since its inception 20 years ago, this conference has been the premier venue for the newest research and technological trends that aid in studying the molecular “machines” inside the human body. These biological elements ensure faithful DNA replication and expression of genes to create the many proteins that make up a cell.

This conference will cover all aspects that govern the central building blocks of life, DNA replication, transcription, and translation, as well as activities that impact these processes such as DNA repair, DNA editing, and RNA editing. There will be a special emphasis on how they work, how they interact with one another, and how they may be used as diagnostic tools or as targets for novel therapies.

Goals and Takeaways

· The molecular machines at work during DNA replication, transcription, translation, DNA repair, and gene modification. 

· The latest technologies in structural, biophysical, and biochemical technologies to study molecular machines.

· Opportunities for therapeutic targeting of nucleic-associated molecular machines.

Program Topics

· DNA replication

· Transcription

· Translation

· DNA repair

· Gene modification

· Machines and medicines

Workshops

Two Meet the Expert lunch sessions will be held where students, postdocs, and other early-career researchers will discuss science topics in small groups with leading experts from the field.

A Career Development Workshop will be held for early-career scientists to discuss professional pathways in academia, government, and industry in a panel format.

Keynote Speakers

John Kuriyan
Geeta Narlikar

John Kuriyan, PhD
Dean of School of Medicine Basic Sciences
Vanderbilt University
Nashville, TN
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Geeta Narlikar, PhD
Chair, Department of Biochemistry and Biophysics
University of California, San Francisco, CA
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James R. Williamson, PhD
Professor, Scripps Research Institute, La Jolla, CA
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Wei Yang

Wei Yang, PhD
Distinguished Investigator
NIH, Bethesda, MD
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Location and Venue

Millennium Maxwell House

2025 Rosa L. Park Boulevard
Nashville, TN 37228
USA

Important Dates

Abstract Submission Deadline: Sunday, April 6, 2025

Early Registration Deadline: Monday, April 28, 2025

Housing Deadline: May 4, 2025

Registration Cancellation Deadline: Monday, April 28, 2025

Regular Registration Deadline: Sunday, May 11, 2025

Conference Organizers

Meindert Lamars

Meindert Lamers, PhD
Associate Professor
Leiden University Medical Center, Leiden, The Netherlands
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Lisa Racki

Lisa Racki, PhD
Assistant Professor
The Scripps Research Institute, La Jolla, CA
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Blake Wiedenheft

Primary Organizer: Blake Wiedenheft, PhD
Professor
Montana State University, Bozeman, MT
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